Everything You Need To Know About Glutathione, - The Ultimate Solution To Whiter Skin In 2 Weeks

If you have dreamt of having a snow-white complexion and skin, Glutathione is the wonder drug for you.


One of the latest craze in the skin and beauty industry. This skin whitening product is available in a wide range of pills, soaps, creams, lotions, and even intravenous injections.

What is Glutathione?

Glutathione is a tripeptide of cysteine, glycine, and glutamate. It is an antioxidant naturally found in human cells that neutralizes free radicals, boosts the immune system and detoxifies the body.


This is because it frees up other antioxidants in your diet--such as Vitamin E and Vitamin C--to allow them to eliminate other free radicals.

 It can also cause skin lightening by converting melanin to a lighter color and deactivating the enzyme tyrosinase, which helps produce the pigment.

What are the body functions of Glutathione?

Glutathione is a powerful antioxidant found in every cell in the body. One unique thing about glutathione is that the body is able to make it in the liver, which is not true of most antioxidants. It is made of three types of molecules known as amino acids.

Glutathione has many important functions, including:

  • making DNA, the building blocks of proteins and cells

  • supporting immune function

  • forming sperm cells

  • breaking down some free radicals

  • helping certain enzymes function

  • regenerating vitamins C and E

  • transporting mercury out of the brain

  • helping the liver and gallbladder deal with fats

  • assisting regular cell death (a process is known as apoptosis)

What are the natural sources of Glutathione?

Glutathione contains sulfur molecules, which may be why foods high in sulfur help to boost its natural production in the body. These foods include:

  • cruciferous vegetables, such as broccoli, cauliflower, Brussels sprouts

  • Allium vegetables, such as garlic and onions

  • eggs

  • nuts

  • legumes

  • lean protein, such as fish, and chicken

Is Glutathione Safe?

Glutathione is available for oral, topical and intravenous routes. While the safety and effectiveness of oral and topical glutathione has been established. Not enough research studies have been done to demonstrate the safety of intravenous glutathione.


In fact, in countries like the Philippines, the use of intravenous Glutathione for skin lightening has been banned due to side effects.  There have been reports of serious skin disorders, thyroid function impairment, and kidney dysfunction.


In the United States, The Food and Drug Administration issued an advisory on the dangers of unregulated injectable skin-lightening agents sold online and in stores, but it hasn’t taken a stance on treatments provided by medical professionals.


How does Glutathione   Whiten Your Skin?

  • It is a great antioxidant, hence removes the toxins really well.

  • Glutathione lightens and brightens the skin tone

  • Induces a glow and improves the texture

  • Glutathione reduces skin pigmentation, age spots, blemishes, ulcers, dark circles, freckles, etc.

  • No more pimples and wrinkles

  • It takes 3months to 6 months of taking tablets to start showing effects.

  • The effect of creams and lotions is more delayed and variable.

It is not that simple. These effects of Glutathione are created on a temporary basis, and once you discontinue the intake, the skin complexion will eventually go back to its original tone.


What are the dosage and side effects of Glutathione Pills?

The dosage of glutathione pills is 500mg to 1gm daily. Effects are superior with combining use with Vitamin C(1000mg) which is also an antioxidant. Side Effects are as below:

  • abdominal cramps.

  • bloating.

  • trouble breathing due to bronchial constriction.

  • allergic reactions, such as rash

What is the dosage and side effects of intravenous Glutathione?

There is inadequate safety documentation on the use of high doses of glutathione administered at 600 mg to 1.2 grams once weekly and even up to twice weekly. 


Adverse drug reactions resulting from the use of glutathione IV for skin whitening have been reported and include the following:

1. Reports of adverse drug reactions ranging from skin rashes to the serious and potentially fatal Steven Johnsons Syndrome and Toxic Epidermal Necrolysis.

2. Derangements in the thyroid function

3. Suspected kidney dysfunction potential resulting in kidney failure.

4. Severe abdominal pain in a patient receiving twice-weekly glutathione administered intravenously had been reported.

5. An incorrect technique in intravenous administration, especially in association with administration by untrained persons, can result in the following:


  • Introduction of harmful microorganisms that can result in serious infections including potential fatal sepsis.

  • Injection of air can lead to embolus which is also potentially fatal.

  • Unsafe use of needles (recycling, sharing) can result in the transmission of hepatitis B and even HIV.

  • Counterfeiting of glutathione has been reported and may lead to the use of non-sterile preparations which could lead to serious infections.

How does topical Glutathione lotion whiten and brighten skin?

Thanks to its melanin-inhibiting properties, reduced glutathione has become a popular oral option to whiten and brighten skin.


However, researchers recently uncovered a similar topical application for glutathione’s oxidized form that’s showing promising results. 


In a recent study, 30 Filipino women aged 30–50 years applied 0.5 g of oxidized glutathione lotion to one side of their face and a placebo lotion to the opposite side twice daily for 10 consecutive weeks.


The study was randomized, matched-paired, and double-blinded. Skin whitening, moisture, firmness, and smoothening, as well as wrinkle reduction, were objectively measured every week by researchers. Researchers and subjects also subjectively rated their skin along with similar criteria.


Over the course of 10 weeks, average melanin index values quantified by a Mexameter MX18, corresponding to skin whiteness, decreased nearly 30 points on sites that received oxidized glutathione lotion, while the placebo sites saw only a slight decrease.


Glutathione sites also had an increase in moisture and smoothness over placebo sites, as well as a reduction in wrinkles. Skin firmness did not appear affected by glutathione.


Until now, reduced glutathione was used to brighten skin by oral administration, but was ill-suited for topical application because it is unstable in aqueous form. Fortunately, oxidized glutathione is stable in aqueous form and is able to be used in lotions or creams.

How soon will my skin start looking whiter?

It can take up to six months to see the benefits of glutathione and the results vary for each individual according to their body constitution.


 Glutathione for skin whitening procedure depends on the metabolic response of individuals. Some might see the result in as early as two weeks, while some may take longer.

What are the other skin benefits of topical Glutathione?

Glutathione has another great skin benefit. Anti-aging. The most common cause of skin aging is photoaging.

Photoaging is caused by repeated exposure to UV light from the sun. UV rays produce a substance called free radicals which damage our skin cells and causes early aging.

This typically results in:

  • Wrinkles and fine lines

  • Uneven pigmentation resulting in things like freckles and age spots

  • Loose rough skin 

  • Visible capillaries

Worried about free radical damage? Have no fear, glutathione is an antioxidant that will protect your body from free radicals. 


10-week study was created to measure the effects of glutathione. After applying glutathione to their faces participants found there was a clear decrease in pigmentation. The overall moisture content of their skin improved and wrinkles were significantly reduced. 


Which are the recommended American brands of oral Glutathione?

Based on a survey by MSN, the following are the top brands of Glutathione in the USA

  • Jarrow Formulas was founded in 1977 and is based in Los Angeles, California. They make a wide range of nutritional supplements, probiotics, amino acids, enzymes, and more. Among their antioxidants, they sell glutathione veggie caps is a variety of formulas.

  • Now Foods makes food supplements, essential oils, natural and organic beauty products, and more. They were established in 1968 in Bloomingdale, Illinois by Dr. Elwood Richards, as a rebranding of the older company “Dr. Fearn’s Soy-O Foods”. They strive to make health food supplements that are organic and natural, and yet still affordable. 

  • Core Med Science was founded by Dr. Bogdan Popa in 2014 and is based in Costa Mesa, California. They make glutathione supplements in both liquid and soft gel forms. They use liposomes to carry the main ingredient of their dietary supplements. 


Which are the top American cosmetics with Glutathione?


Based on a survey by MSN

Skin whitening soap: There are also soaps that contain anti-oxidants and anti-aging ingredients--and glutathione is one of the main ingredients.


For example, Shouvy’s Pure Glutathione Whitening Bleaching Soap uses coconut oil, Vitamin B3 and C, radish extract and rice milk extract. It can make your skin look younger and remove blemishes, freckles, pimples, and melasma.



 As the body ages, it produces less glutathione. There are patches of glutathione which supplement the body’s glutathione and can counter the effects of aging.

It helps detoxifies the body with its organic amino acids. An example is the PatchMD Glutathione Patch. You wear it for 8 hours a d 


You can find Glutathione in liquid form. An example is Liposomal Glutathione Liquid by Core Med Science.

They use liposomal Glutathione, which means that the Glutathione is encapsulated in such a way that it will not be destroyed by stomach acids and digestive juices.

This way, it will only get released when it reaches the small intestine and it has the same effect as taking oral supplements.


Topical Cream: 

You can also find topical creams that contain glutathione, such as Perricone MD’s Rejuvenating Moisturizer.

They are used to remove blemishes and give you an evener skin tone, as well as remove wrinkles and other symptoms of aging skin.

So, now you need to look no further for fairer and brighter skin! Get used to admiring looks and compliments with your new look. Do put down your very own personal experience in the comments section and your questions too!

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